Colchicine Treatment for Recurrent Pericarditis
نویسندگان
چکیده
منابع مشابه
Recurrent pericarditis. Relief with colchicine.
Recurrence is one of the major complications of pericarditis. Treatment of recurrence is often difficult, and immunosuppressive drugs or surgery may be necessary. We conducted an open-label prospective study of nine patients (seven men and two women; age, 18-64 years; mean age, 41.7 +/- 13.7 years). Patients were treated with colchicine (1 mg/day) to prevent recurrences. All patients had suffer...
متن کاملColchicine for the prevention of recurrent pericarditis.
The most troublesome complication of acute pericarditis is recurrent episodes of pericardial inflammation, which occur in 15-32% of cases. It was recently found that viral infection has a major role, but in many cases the cause is unknown. The optimal method for prevention has not been fully established; accepted modalities include non-steroidal anti-inflammatory drugs, corticosteroids, immunos...
متن کاملFirst line treatment with colchicine reduced recurrent pericarditis.
M e t h o d s Design: Randomized controlled trial (COlchicine for REcurrent pericarditis [CORE] trial). Allocation: {Concealed}†.* Blinding: Blinded {data collectors, outcome assessors, monitoring committee, and data analysts}†.* Follow-up period: Mean 20 months (range 8 to 44 mo). Setting: A hospital in Torino, Italy. Patients: 84 patients ≥ 18 years of age (mean age 54 y, 65% women) who had a...
متن کاملColchicine as first-choice therapy for recurrent pericarditis: results of the CORE (COlchicine for REcurrent pericarditis) trial.
BACKGROUND Colchicine seems to be a good drug for treating recurrences of pericarditis after conventional treatment failure, but no clinical trial has tested the effects of colchicine as first-line drug for the treatment of the first recurrence of pericarditis. METHODS A prospective, randomized, open-label design was used to investigate the safety and efficacy of colchicine therapy as adjunct...
متن کاملColchicine for recurrent pericarditis (CORP): a randomized trial.
BACKGROUND Recurrence is the most common complication of pericarditis, affecting 10% to 50% of patients. OBJECTIVE To evaluate the efficacy and safety of colchicine for the secondary prevention of recurrent pericarditis. DESIGN Prospective, randomized, double-blind, placebo-controlled multicenter trial. (ClinicalTrials.gov registration number: NCT00128414) SETTING: 4 general hospitals in ur...
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ژورنال
عنوان ژورنال: Circulation
سال: 1998
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.97.21.2183